The USP18 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to USP18. This antibody recognizes Homo Sapiens, and Human antigen. The USP18 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. Isoform 2: Has enzymatic activity similar to isoform 1 and interferes with type I interferon signaling. Major deISGylation enzyme for nuclear proteins(PubMed:22170061)